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Chang, Emmanuel

Chang, Emmanuel

Professor and Chair


Phone: 718-262-3778
Office Location: AC-3F01G

Research in the lab of Emmanuel Chang centers around biological applications of mass spectrometry. Our major interest is in analysis and methods development for protein phosphorylation and other post-translational modifications. Applications include phosphorylation in cell cycle; ADP-ribosyltaion; mass spectrometry-based biosensors, and kinase inhibitors and enzyme kinetics. We also collaborate with other CUNY and external scientists who would like to harness the power of mass spectrometry to study there own interesting biological systems.

We supplement our experimental work with computational methods including bioinformatic protein sequence analysis and molecular modeling.

Dr. Chang's teaching interests include analytical chemistry, biochemistry, writing and data presentation, literature analysis, and innovations in introductory chemistry.

Office Hours

Monday2:00 PM - 2:50 PM
Wednesday11:00 AM - 11:50 AM


PhD The Rockefeller University Biochemistry 2006 
BA Princeton University Chemistry 1999 

Areas of Expertise

  • Biochemistry
  • Analytical Chemistry
  • Mass Spectrometry
  • Proteomics
  • Bioinformatics
  • Phosphorylation
  • Cell Cycle
  • Chemical and Biochemical
  • Chemical Education
  • Introductory Chemistry
  • Instrumental Analysis

Publications in Field Of Expertise



Professional Honors, Prizes, Fellowships

  • Dean's Award for Undergraduate Research Engagement: 2014.
  • Provost's Award for Undergraduate Research Engagement: 2013.
  • Sigma Alpha Pi Excellence in Teaching Award: 2008.
  • Burroughs-Wellcome Interfaces in Science Award: 1999-2003.
  • American Institute of Chemists Award: 1999.


  • Professional Staff Congress-CUNY, The Role of Protein Phosphorylation in the Proliferation and Pathogenesis of Zika. 7/2017 - 8/2018: $6,000.
  • Professional Staff Congress-CUNY, A Global Approach to the Discovery of HIV Protein Phosphorylation by Host Cell Kinases. 7/2015 - 6/2016: $6,000.
  • Professional Staff Congress-CUNY, How is HIV Reverse Transcripatse Regulated by Cyclin Dependent Kianse Phosphorylation?. 7/2014- 6/2015: $3,500.
  • Professional Staff Congress-CUNY, Regulation of HIV Reverse Transcriptase by Cyclin Dependent Kinase Phosphorylation. 7/2013 - 12/2014: $6,000.
  • Professional Staff Congress-CUNY Round 42, Cyclin Specificity Using a Novel Mass Spectrometric Quantitative Mulitisite Phosphorylation Assay. 7/2011 - 12/2012: $6,000.
  • ARRA Supplement to NIH MBRS SCORE Grant, Using isotope labeling/mass spectrometry to probe Cdk1 multisite phosphorylation dynamics. 10/2010 - 6/2012: $160,000.
  • Collaborative Incentive Research Grant-CUNY, Round 16, Proteomic Analysis of Nup211p. 9/2010 - 8/2012: $60,000.
  • Luitpold Pharmaceuticals, Pharmaceutical Compound Analysis. 1/2010- 12/2012: $750.
  • Research Corporation Cottrell College Science Award, Investigating the gas phase chemistry of phosphorylated peptide ions using mass spectrometry. 2/2009 - 1/2011: $45,000.
  • National Institutes of Health-MBRS/SCORE, Using isotope labeling/mass spectrometry to probe Cdk1 multisite phosphorylation dynamics. 1/2009 - 1/2012: $460,000.
  • York College Auxiliary Enterprises, Developing Career Paths in Natural Science. 8/2007 - 12/2007: $700.
  • Professional Staff Congress-CUNY, Round 39, Understanding mass spectrometric phosphopeptide behavior for bioanalytical methods development. 7/2008 - 6/2009: $5,000.
  • Professional Staff Congress-CUNY, Round 38, Improving the computational prediction of cyclin-dependent kinase phosphorylation substrates. 7/2007 - 6/2008: $5,500.
  • Research Equipment Grant-CUNY, Probing the dynamics of binding and catalysis in dihydropteridine reductase using a mT-jump stopped-flow device. 3/2007: $40,000.
  • Graduate Research Technology Initiative-CUNY, Quantitative studies on protein interactions and phosphorylation using isoelectronic focusing and. 9/2006 - 8/2007: $120,000.

Offices Held In Professional Societies

  • Session organizer, Biological Spectroscopy, 44th Annual Middle Atlantic Regonal Meeting of the American Chemical Society: 5/2015.
  • Board of Directors, Analytical Topical Group, New York Section of the American Chemical Society: 8/2008 - present.
  • Session co-organizer, Biological Spectroscopy, 40th Annual Middle Atlantic Regional Meeting of the American Chemical Society, Bayside, NY: 5/2008.