Jha, Bijay

Phone: 718-262-2811
Office Location: SC-008
Email: bjha@york.cuny.edu

Bijay Jha, PhD is an Assistant Professor in the Department of Health Professions at York College, City University of New York. Dr. Jha received his PhD in Molecular Parasitology from Kyungpook National University, South Korea in 2012. He received his Bachelor’s in Medical Laboratory Science and Master’s in Medical Microbiology in Nepal. After completing his postdoctoral studies from Ohio State University, he joined York College/CUNY in the year 2021. Dr. Jha’s research focuses on the molecular mechanism of pathogenesis in Chagas disease. He studies the role of host autophagy against Trypanosoma cruzi infection.

Curriculum Vitae

Office Hours

Day	Time
Tuesday	10:00 AM to 12:00 Noon
Wednesday	10:00 AM to 12:00 Noon

Education

Degree	Institution	Field	Dates
PhD	Kyungpook National University	Molecular Parasitology	2012
MS	Kathmandu University	Medical Microbiology	2003
BS	Tribhuvan University	Medical Laboratory Science	2000

Areas of Expertise

Medical Laboratory Science
Microbiology
Molecular Biology
Immunology

Publications in Field Of Expertise

Books

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Articles

Jha BK, Varikuti S, Verma C, Shivahare R, Bishop N, Pedroso G, MacDonald J, Sur A, Myler PJ, Schenkman S, Satoskar AR, McGwire BS. "Immunization with a Trypanosoma cruzi cyclophilin-19 deletion mutant protects against acute Chagas disease in mice." npj Vaccines. 8(1) 2023: 63.

Dos Santos GP, Abukawa FM, Souza-Melo N, Alcântara LM, Bittencourt-Cunha P, Moraes CB, Jha BK, McGwire BS, Moretti NS, Schenkman S. "Cyclophilin19 secreted in the host cell cytosol by Trypanosoma cruzi promotes ROS production required for parasite growth." Cellular Microbiology. 23(4) 2021: e13295.

Jha BK*, Sanjay Varikuti*, Erin A. Holcomb*, Jodi C. McDaniel, Manjula Karpurapu, Nidhi Srivastava, Bradford S. McGwire, Abhay R. Satoskar Narasimha L. Parinandi.. "Role of vascular endothelium and exosomes in human protozoan parasitic diseases." Vessel Plus. 4:28 2020: .

Jha BK*, Sanjay Varikuti*, Gabriella R. Seidler, Greta Volpedo, Abhay R. Satoskar, Bradford S. McGwire. "MicroRNA-155 deficiency exacerbates Trypanosoma cruzi infection." Infection and Immunity. 88(7) 2020: e00948-19.

Varikuti S, Singh B, Volpedo G, Ahirwar DK, Jha BK, Saljoughian N, Hamza O, Halsey G, Holcomb EA, Maryala RJ, Oghumu S, Ganju RK and Satoskar AR.. "Ibrutinib treatment inhibits breast cancer progression and metastasis by inducing conversion of myeloid-derived suppressor cells to dendritic cells." British Journal of Cancer. 122(7) 2020: 1005-1013.

Jha BK*, Varikuti S*, Volpedo G*, Ryan N, Hasley G, Hamza O, McGwire B, Satoskar A. "Host-Directed drug therapies for Neglected Tropical Diseases caused by protozoan parasites." Frontiers in Microbiology. 30 (9) 2018: .

Jha BK, Jung HJ, Seo I, Suh SI, Suh MH, Baek WK. "Juglone induces cell death of Acanthamoeba through increased production of reactive oxygen species." Experimental Parasitology. 159 2015: 100-106.

Jha BK, Seo I, Kong HH, Suh SI, Suh MH, Baek WK. "Tigecycline inhibits proliferation of Acanthamoeba castellanii." Parasitology Research. 114 (3) 2015: 1189-1195.

Jha BK, Jung HJ, Seo I, Kim HA, Suh SI, Suh MH, Baek WK. "Chloroquine has cytotoxic effect in encysting Acanthamoeba through modulation of autophagy." Antimicrobial Agents and Chemotherapy. 58(10) 2014: 6235-6241.

Park JY, Jung HJ, Seo I, Jha BK, Suh SI, Suh MH, Baek WK. "Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway." Cellular Oncology. 37(4) 2014: 269-279.

Seo I, Jha BK, Suh SI, Suh MH, Baek WK. "Microbial Profile of the Stomach: Comparison between Normal Mucosa and Cancer Tissue in the Same Patient." Journal of Bacteriology and Virology. 44(2) 2014: 162-169.

Seo I, Jha BK, Lim JG, Suh SI, Suh MH, Baek WK. "Identification of lysosomotropic compounds based on the distribution and size of lysosomes." Biochemical and Biophysical Research Communicationsl. 450 (1) 2014: 189-194.

Jung HJ, Seo I, Jha BK, Suh SI, Suh MH, Baek WK. "Minocycline inhibits angiogenesis in vitro through the translational suppression of HIF-1α." Archives of Biochemistry and Biophysics. 545 2014: 74-82.

Yang HW, Lee YR, Inoue N, Jha BK, Danne DB, Kim HK, Lee J, Goo YK, Kong HH, Chung DI, Hong Y. "Loop-mediated isothermal amplification targeting 18S ribosomal DNA for rapid detection of Acanthamoeba." Korean Journal of Parasitology. 51 (3) 2013: 269-277.

Jeong S, Yang HW, Yoon YR, Lee WK, Lee YR, Jha BK, Sylvatrie-Danne DB, Kim S, Jeong C, Kong HH, Goo YK, Hong Y, Chung DI. "Evaluation of the efficacy of chloroquine chemoprophylaxis for vivax malaria among Republic of Korea military personnel." Parasitology International. 62 2013: 494-496.

Lee JY, Song SM, Moon EK, Lee YR, Jha BK, Danne DB, Cha HJ, Yu HS, Kong HH, Chung DI, Hong Y. "Cysteine protease inhibitor (AcStefin) is required for complete cyst formation of Acanthamoeba." Eukaryotic Cell. 12 (4) 2013: 567-574.

Song SM, Han BI, Moon EK, Lee YR, Yu SH, Jha BK, Danne DB, Kong HH, Chung DI, Hong Y. "Autophagy protein 16-mediated autophagy is required for the encystation of Acanthamoeba castellanii." Molecular and Biochemical Parasitology. 183(2) 2012: 158-165.

Seok JW, Lee YS, Moon EK, Lee JY, Jha BK, Kong HH, Chung DI, Hong Y. "Expressed sequence tag analysis of the erythrocytic stage of Plasmodium berghei." Korean Journal of Parasitology. 49(3) 2011: 221-228.

Song SM, Shin JW, de Guzman JV, Kim J, Yu HS, Jha BK, Kong HH, Hong Y, Chung DI. "Paragonimus westermani: identification and characterization of the fasciclin I domain-containing protein." Experimental Parasitology. 125(2) 2010: 76-83.

Lee JY, Song SM, Seok JW, Jha BK, Han ET, Song HO, Yu HS, Hong Y, Kong HH, Chung DI. "M17 leucine aminopeptidase of the human malarial parasite Plasmodium vivax." Molecular and Biochemical Parasitology. 170(1) 2010: 45-48.

Chapters

Terrazas C, Oghumu S, Jha BK, Natarajan G, Drew ME, Denkers EY, Satoskar AR, McGwire BS. "Subverting Immunity from the Inside: Strategies of Intracellular Survival- Protozoans." Encyclopedia of Immunobiology. 4 2016: 83-93.

Other

Professional Honors, Prizes, Fellowships

Postdoctoral Research: 2015-2021.

Best poster award- Korean Society of Parasitology: 2012.

KNU Honors Scholarship- PhD (Parasitology): 2009.

Merit Scholarship- MS (Medical Microbiology): 2001.

Merit Scholarship- BS (Medical Laboratory Science): 1997.