Office Location: AC-4E03E
|PhD||Columbia University||Biochemistry and Molecular Biophysics|
|MM||Indiana University (Bloomington)||Viola Performance|
|BS||University of Pittsburgh||Chemistry and Music, summa cum laude|
Areas of Expertise
- Biochemistry and Biophysics
Cell and Molecular Biology
Articles in Field Of Expertise
S Pei, TC Swayne, JF Morris, L Emtage. "Threshold concentration and random collision determine the growth of the phase-separated huntingtin inclusion from a stable core." Communications Biology. 2021: online.
F Aktar, C Burudpakdee, M Polanco, S Pei, TC Swayne, P LipkeL Pon, L Emtage. "The huntingtin inclusion is a dynamic phase-separated compartment." LSA. 2(5) 2019: e201900489.
L Emtage, S Aziz-Zaman, O Padovan, R Horvitz, C Fang-Yen, N Ringstad. "IRK-1 potassium channels mediate peptidergic inhibition of Caenorhabditis elegans serotonin neurons via a Go signaling pathway." J. Neuroscience. 32(46) 2012: 16285-16295.
A Bounoutas, J Kratz, L Emtage, C Ma, K Nguyen, and M Chalfie. "Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway." PNAS. 108 2011: 3982-3987.
L Emtage, H Chang, R Tiver, C Rongo. "MAGI-1 modulates AMPA receptor synaptic localization and behavioral plasticity in response to prior experience." PLoS One. 4 2009: e4613.
L Emtage, G Gu, E Hartwieg, M Chalfie. "Extracellular proteins organize the mechanosensory channel complex in C. elegans touch receptor neurons." Neuron. 44 2004: 795-807..
Presented Papers, Lectures, and Exhibitions and Performances
" Concentration-dependent growth and dispersion of a phase-separated inclusion of unfolded protein in vivo " 2020: Levich Institute Seminar Series.
" Nucleation and Growth of a Phase-separated Huntingtin Inclusion " 2019: American Society of Cell Biology Annual Meeting.
" Using mutant huntingtin to probe the nature and formation of unfolded protein inclusions in yeast " 2019: NYC Yeast Meeting.
" The unfolded Huntingtin protein inclusion in S. cerevisiae is a non-membrane bound fluid compartment with novel properties " 2017: City College Biology Colloquium.
" Decoupling and Recoupling: the Important Distinctions between Program Assessment and Course Assessment " 2017: Drexel Annual Conference on Teaching and Learning Assessment.
" MAGI-1 modulates behavioral plasticity and glutamate receptor synaptic localization " 2008: C. elegans Neuronal Development, Synaptic Function, and Behavior Meeting.
" MAGI-1 modulates behavioral plasticity and glutamate receptor synaptic localization " 2007: CSHL Meeting on Synapses: From Molecules to Circuits and Behavior.
" ceMAGI-1 modulates behavioral plasticity and glutamate receptor synaptic localization " 2006: Society for Neuroscience.
" The evolving model of mechanosensory transduction in C. elegans " 2005: East Coast Nerve Network, invited speaker.
" Mechanosensory complex interactions with the extracellular matrix " 2002: East Coast Worm Meeting.
Professional Honors, Prizes, Fellowships
National Academies Education Fellow in the Sciences: 2015-2016.
Charles and Johanna Busch Fellowship: 2007-2008.
American Heart Association Postdoctoral Fellowship: 2005-2007.
National Science Foundation Summer Training Fellowship: .
Richard King Mellon Foundation Scholar: .
National Institute of Health, In vivo targeting of unfolded protein to a phase-separated Huntingtin inclusion. 2020-2024: $493,009.
PSC-CUNY Research Award, Identifying the contents of an unfolded protein inclusion body. 2020-2021: $3,500.
PSC-CUNY Research Award, Characterizing the molecular mechanisms underlying inclusion body formation. 2019-2020: $3,500.
National Institute of Health, Cellular mechanisms underlying detoxification of mutant Huntingtin. 2016-2019: $457,359.
US Department of Defense, Co-PI, High-Sensitivity Imaging for Molecular and Cellular Biology. 2017: $508,473.50.
PSC-CUNY Research Award, Identifying factors that contribute to the aggregation and removal of mutant Huntingtin. 2017-2018: $3,500.
PSC-CUNY Research Award, Investigation into the role of chaperone protein Hsp42 in Huntingtin protein aggregation. 2015-2016: $3,500.
Pace University, Small heat shock proteins are required for the formation of polyQ-Huntingtin inclusion bodies. 2013-2014: $1,500.
American Heart Association, Characterization of MAG-1, a Synaptic Scaffolding Protein Required for Glutamate Receptor Localization. 2005-2007: $80,000.
Other Professional Activities and Public Service
Ad Hoc Reviewer, Nature Communications, Nature Chemical Biology, Computational and Structural Biotechnology, Biophysical Journal, CourseSourse: 2016 - present.
American Society for Cell Biology member: 2014 - present.
Society for Developmental Biology member: 2015 - present.
Judge, Junior Mathematics, Science and Humanities Symposium: 2015 - 2019.
Judge, TriBeta National Biological Honor Society NE-1 Convention: 2014.