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Emtage, Lesley

Overview

Curriculum Vitae

  1. Education


    Degree Institution Field Dates
    PhD  Columbia University  Biochemistry and Molecular Biophysics   
    MM  Indiana University (Bloomington)  Viola Performance   
    BS  University of Pittsburgh  Chemistry and Music, summa cum laude   
  2. Full-Time Academic Experience


    Institution Rank Field Dates
    York College CUNY  Assistant Professor  Biology  August 2014 - present 
    New York University Langone Medical Center  Postdoctoral Researcher  Molecular and Cellular Neurobiology  June 2010 - May 2012 
    Rutgers University  Postdoctoral Researcher  Genetics  June 2004 - January 2010 
  3. Part-Time Academic Experience


    Institution Rank Field Dates
    College of Mount Saint Vincent  Adjunct Assistant Professor  Genetics  August 2013 - July 2014 
    Purchase College SUNY  Lecturer  Cell Biology  Spring 2014 
    Pace University  Adjunct Assistant Professor  Biology  May 2012 - December 2013 
  4. Non Academic Experience


  5. Employment Record At This Institution

    Rank Dates
    Assistant Professor in Biology  August 2014 - present 
  6. Publications In Field Of Expertise

    1. Books:
    2. Papers in Professional Journals:
      1. Articles:

        F Aktar, C Burudpakdee, M Polanco, S Pei, TC Swayne, P LipkeL Pon, L Emtage. "The huntingtin inclusion is a dynamic phase-separated compartment." LSA. 2(5) 2019: e201900489.

        L Emtage, S Aziz-Zaman, O Padovan, R Horvitz, C Fang-Yen, N Ringstad. "IRK-1 potassium channels mediate peptidergic inhibition of Caenorhabditis elegans serotonin neurons via a Go signaling pathway." J. Neuroscience. 32(46) 2012: 16285-16295.

        A Bounoutas, J Kratz, L Emtage, C Ma, K Nguyen, and M Chalfie. "Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway." PNAS. 108 2011: 3982-3987.

        L Emtage, H Chang, R Tiver, C Rongo. "MAGI-1 modulates AMPA receptor synaptic localization and behavioral plasticity in response to prior experience." PLoS One. 4 2009: e4613.

        L Emtage, G Gu, E Hartwieg, M Chalfie. "Extracellular proteins organize the mechanosensory channel complex in C. elegans touch receptor neurons." Neuron. 44 2004: 795-807..

      2. Proceedings:
        1. Refereed Proceedings
        2. Non-Refereed Proceedings
    3. Chapters in Books:
    4. Government Reports or Monographs
    5. Book Reviews:
  7. Other Publications

    1. Books:
    2. Papers in Professional Journals:
      1. Articles:

        L Emtage, L Bradbury, N Coleman, D Devenport, A Dunning, J Grew. "Cell Signaling Pathways – a case study approach." CourseSource. 2016: online.

      2. Proceedings:
        1. Refereed Proceedings
        2. Non-Refereed Proceedings
    3. Chapters in Books:
    4. Government Reports or Monographs
    5. Book Reviews:
  8. Presented Papers, Lectures, And Exhibitions And Performances

    "Concentration-dependent growth and dispersion of a phase-separated inclusion of unfolded protein in vivo" 2020: Levich Institute Seminar Series.

    "Nucleation and Growth of a Phase-separated Huntingtin Inclusion" 2019: American Society of Cell Biology Annual Meeting.

    "Using mutant huntingtin to probe the nature and formation of unfolded protein inclusions in yeast" 2019: NYC Yeast Meeting.

    "The unfolded Huntingtin protein inclusion in S. cerevisiae is a non-membrane bound fluid compartment with novel properties" 2017: City College Biology Colloquium.

    "Decoupling and Recoupling: the Important Distinctions between Program Assessment and Course Assessment" 2017: Drexel Annual Conference on Teaching and Learning Assessment.

    "MAGI-1 modulates behavioral plasticity and glutamate receptor synaptic localization" 2008: C. elegans Neuronal Development, Synaptic Function, and Behavior Meeting.

    "MAGI-1 modulates behavioral plasticity and glutamate receptor synaptic localization" 2007: CSHL Meeting on Synapses: From Molecules to Circuits and Behavior.

    "ceMAGI-1 modulates behavioral plasticity and glutamate receptor synaptic localization" 2006: Society for Neuroscience.

    "The evolving model of mechanosensory transduction in C. elegans" 2005: East Coast Nerve Network, invited speaker.

    "Mechanosensory complex interactions with the extracellular matrix" 2002: East Coast Worm Meeting.

  9. Patents

    None

  10. Work In Progress

    1. Books in progress:
    2. Papers in Progress:

      S Pei, D Kone, S Singh and L Emtage. "Chaperone systems cooperate to target unfolded protein to the inclusion body." . : .

    3. Papers submitted to journals for consideration:

      S Pei, TC Swayne, JF Morris, L Emtage. "Threshold concentration and random collision determine the growth of the phase-separated huntingtin inclusion from a stable core." . : .

    4. Research in progress:
  11. Professional Honors, Prizes, Fellowships

    National Academies Education Fellow in the Sciences: 2015-2016.

    Charles and Johanna Busch Fellowship: 2007-2008.

    American Heart Association Postdoctoral Fellowship: 2005-2007.

    National Science Foundation Summer Training Fellowship: .

    Richard King Mellon Foundation Scholar: .

  12. Grants-In-Aid

    National Institute of Health, In vivo targeting of unfolded protein to a phase-separated Huntingtin inclusion. 2020-2024: $493,009.

    PSC-CUNY Research Award, Identifying the contents of an unfolded protein inclusion body. 2020-2021: $3,500.

    PSC-CUNY Research Award, Characterizing the molecular mechanisms underlying inclusion body formation. 2019-2020: $3,500.

    National Institute of Health, Cellular mechanisms underlying detoxification of mutant Huntingtin. 2016-2019: $457,359.

    US Department of Defense, Co-PI, High-Sensitivity Imaging for Molecular and Cellular Biology. 2017: $508,473.50.

    PSC-CUNY Research Award, Identifying factors that contribute to the aggregation and removal of mutant Huntingtin. 2017-2018: $3,500.

    PSC-CUNY Research Award, Investigation into the role of chaperone protein Hsp42 in Huntingtin protein aggregation. 2015-2016: $3,500.

    Pace University, Small heat shock proteins are required for the formation of polyQ-Huntingtin inclusion bodies. 2013-2014: $1,500.

    American Heart Association, Characterization of MAG-1, a Synaptic Scaffolding Protein Required for Glutamate Receptor Localization. 2005-2007: $80,000.

  13. Institutional Service

    1. Service to the Department

      Member, Biology Department Assessment Committee: 2018-present.

      Member, Biology Department Search Committee: 2019.

      Member, Biology Department Academic Program Review Committee: 2018-19.

      Strategic Planning/Assessment Liaison: 2015-18.

    2. Service to the School

      Member, Search Committee, Earth and Physical Sciences: 2017.

    3. Service to the College

      Parliamentarian, York College Curriculum Committee: 2020-present.

      Member, York College Governance Committee: 2020-present.

      Member, York College Senate: 2018-20.

      Parliamentarian, York College Faculty Caucus: 2019-20.

      Secretary, Committee on Instruction and Professional Development: 2019-20.

      Parliamentarian, York College Senate: 2018-19.

      Member, Committee on Instruction and Professional Development: 2018-19.

      Panel Moderator, York College 10th Undergraduate Research Day: 2019.

      Chief Judge, Junior Science and Humanities Symposium: 2018 and 2019.

      Member, Teacher Education Unit Council Advisory Board: 2018 and 2019.

      Faculty Marshal, Commencement: 2018 and 2019.

      Chair, Committee on Instruction and Professional Development: 2017-18.

      Secretary, Committee on Instruction and Professional Development: 2016-17.

      Judge, Junior Science and Humanities Symposium: 2015-17.

    4. Service to the Graduate Center

      Acting York College Representative, Executive Committee, Ph.D. Program in Biology: Spring, 2019.

      Reviewer, Doctoral Student Research Grant Proposals: 2017, 2019, 2020.

    5. Service to the University

      Senator, University Faculty Senate: 2020-present.

      Breakout Session Leader, CUNY NIH SCORE Application Workshop: 2019.

      Alternate Senator, University Faculty Senate: 2017-18.

  14. Offices Held In Professional Societies

  15. Other Professional Activities And Public Service

    Ad Hoc Reviewer, Nature Communications, Nature Chemical Biology, Computational and Structural Biotechnology, Biophysical Journal, CourseSourse: 2016 - present.

    American Society for Cell Biology member: 2014 - present.

    Society for Developmental Biology member: 2015 - present.

    Judge, Junior Mathematics, Science and Humanities Symposium: 2015 - 2019.

    Judge, TriBeta National Biological Honor Society NE-1 Convention: 2014.

  16. Teaching Activities At This Institution

    1. Courses Taught (List)
      Course Description
      BIO 452  Developmental Biology 
      BIO 320  Cell Biology 
      BIO 202L  Biological Principles II Lab 
      BIO 265L  Clinical Microbiology Lab 
      BIO 490  Independent Study 
      BIO 491  Independent Study 
      BIOL (Graduate Center ) 71013  Molecular Biology 
    2. New courses/programs developed (list):