Bradbury, Louis
 

Bradbury, Louis

Curriculum Vitae

Assistant Professor
Biology

Phone: 718-262-5131
Office Location: AC-4E03
LBradbury@york.cuny.edu

Office Hours  
Thursday  2-5pm 

Education

Degree Institution Field Dates
PhD  Southern Cross University  Genetics & Biochemistry  2009 
  Flinders University  Molecular & Microbiology  1999 
BS  Flinders University  Molecular biology & Genetics  1998 
I use comparative genomics and bioinformatic techniques to identify enzymes involved in repair of damaged metabolites and characterize these enzymes using biochemical and genetic approaches. My past research involved the identification and characterization of the gene for fragrance in jasmine and basmati rice and the characterization of genes involved in carotenoid biosynthesis.

Areas of Expertise

Molecular biology
Genetics
Biochemistry
Comparative genomics

Articles in Field Of Expertise

Kunhua Li, Gengnan Li, Louis M.T. Bradbury, Andrew D. Hanson, Steven D. Bruner. "Crystal structure of the homocysteine methyltransferase MmuM from Escherichia coli." Biochemical Journal. 473 (3) 2016: 277-284.

Seaver S, Bradbury LMT, Frelin O, Zarecki R, Ruppin E, Hanson AD, Henry CS. "Improved evidence-based genome-scale metabolic models for maize leaf, embryo, and endosperm." Frontiers in Plant Science. 6 2015: 142.

Bradbury LMT, Ziemak MJ, Elbadawi-Sidhu M, Fiehn O and Hanson AD. "Plant-driven repurposing of the ancient S-adenosylmethionine repair enzyme homocysteine S-methyltransferase." Biochemical Journal. 463 (2) 2014: 279-86.

Seaver SM, Gerdes S, Frelin O, Lerma-Ortiz C, Bradbury LMT, Zallot R, Hasnain G, Niehaus TD, El Yacoubi B, Pasternak S, Olson R, Pusch G, Overbeek R, Stevens R, de Crécy-Lagard V, Ware D, Hanson AD, Henry CS. "High-throughput comparison, functional annotation, and metabolic modeling of plant genomes using the PlantSEED resource." Proc Natl Acad Sci USA. 111 (26) 2014: 9645-50.

Bradbury LMT. "Functional analysis by protein biochemistry." Methods Mol. Biol.. 1099 2014: 147-58.

Bradbury LMT, Niehaus TD, Hanson AD. "Comparative genomics approaches to understanding and manipulating plant metabolism." Curr. Opin. Biotechnol.. 24 (2) 2013: 278-284.

Tzfadia O, Amar D, Bradbury LMT, Wurtzel ET, and Shamir R. "The MORPH Algorithm: Ranking Candidate Genes for Membership in Arabidopsis and Tomato Pathways." Plant Cell. 24 2012: 4389-4406.

Shumskaya M, Bradbury LMT, Monaco R, and Wurtzel ET. "Plastid localization of the key carotenoid enzyme phytoene synthase is altered by isozyme, allelic variation, and activity." Plant Cell. 24 2012: 3725-3741.

Quinlan RF, Shumskaya M, Bradbury LM, Beltrán J, Ma C, Kennelly EJ, Wurtzel ET. "Synergistic interactions between carotene ring hydroxylases drive lutein formation in plant carotenoid biosynthesis." Plant Physiol.. 160 2012: 204-214.

Bradbury LMT, Shumskaya M, Tzfadia O, Wu S, Kennelly EJ and Wurtzel ET. "CruP protects against reactive oxygen species in oxygenic photosynthetic organisms." Proc Natl Acad Sci USA. 109 (27) 2012: E1888-97.

Vallabhaneni R, Bradbury LMT, Wurtzel ET. "The carotenoid dioxygenase gene family in maize, sorghum and rice." Arch Biochem Biophys. 504 2010: 104-111.

Bradbury LMT, Gillies S, Brushett D, Waters DLE, Henry RJ. "Inactivation of an aminoaldehyde dehydrogenase is responsible for fragrance in rice." Plant Mol Biol. 68 2008: 439-49.

Rice N, Cordeirro G, Shepherd M, Bundock P, Bradbury LMT, Pacey T, Furtado A, Henry RJ. "DNA banks and their role in facilitating the application of genomics to plant germplasm." Plant Gen. Res.. 4 2006: 64-70.

Bradbury LMT, Henry RJ, Jin QS, Reinke RF, Waters DLE. "A Perfect marker for fragrance genotyping in rice." Molecular Breeding. 16 (4) 2005: 279-283.

Bradbury LMT, Fitzgerald TL, Henry RJ, Jin QS, Waters DLE. "The gene for fragrance in rice." Plant Biotechnology Journal. 3 2005: 363-370.

Chapters in Field Of Expertise

Bradbury LMT, Henry RJ, Waters DLE. "Flavor development in rice." Biotechnology in flavor production - Blackwell Publishing. 2008: 130-146.

Bradbury LMT, Henry RJ, Waters DLE. "Genotyping for eating quality traits in rice." Advances in plant genotyping - CABI. 2008: 187-194.

Presented Papers, Lectures, and Exhibitions and Performances

" Carotenoid damage and repair " April 13th 2015: Lehman College, CUNY.

" Homocysteine S-methyltransferases: versatile enzymes for S-adenosylmethionine and S-ribosylmethionine repair " 2013: ASPB Plant Biology 2013, Providence, Rhode Island, USA.

" Generation of simple, perfect markers for cereal quality traits " 2007: Molecular markers for plant breeding workshop, Plant and Animal Genome Conference, San Diego, CA.

" Rice gene discovery has sweet smell of success " 2006: Cooperative Research Centre Association Annual Meeting, Brisbane, Australia.

" A perfect marker for fragrance genotyping in rice " 2006: Plant and Animal Genome Conference, San Diego, CA.

Patents

Wurtzel ET and Bradbury LMT. . CruP Protects Against ROS in Oxygenic Photosynthetic Organisms. US Patent 20160060711, filed 05/21/2013, and issued 03/03/2016.

Grain Foods CRC Ltd, Bradbury, LMT, Fitzgerald, TL, Henry, RJ, Jin, Q and Waters, DLE. 2005. Method of producing fragrance by inactivation or reduction of a functional protein with betaine aldehyde dehydrogenase (BADH) activity. AU Patent PCT/AU2005/001458.

Professional Honors, Prizes, Fellowships

iPlant Collaborative travel & lodging grant: 2008.

GrainFoods CRC PhD fellowship: 2004 - 2007.

GrainFoods CRC travel grant: 2007.

GrainFoods CRC travel grant: 2006.

CRC Award for best student presentation: 2006.

Grants-In-Aid

NIH, Identification and Characterization of Carotenoid Repair Enzymes. Awarded. 2016-2019: $300,000.00.

Offices Held In Professional Societies

Member of American Society of Plant Biology: 2013 - present.

Member of the New York Academy of Sciences: 2010 - present.

Member of Sigma Xi (Lehman Chapter): 2011 - 2013.

Committee member of the CUNY Postdoctoral Development Program: 2010 - 2012.

National Academies Education Fellow in the Sciences: June 2015-present.

Other Professional Activities and Public Service

Consultant to Metabolon: Dec 2013.

Outreach to local school: April 2013.

Consultant to Enumeral Biomedical: July 2012.