Simon, Anne

Simon, Anne

Assistant Professor
Biology

Phone: 718-262-2715
Office Location: AC-4E03E
asimon@york.cuny.edu

Office Hours  
by email appointment   
   
Education:
Degree Institution Field Dates
PhD  University of Paris XI, FRANCE  Molecular and Cellular Genetics  1998 
MS  University of Paris XI, FRANCE  Molecular and Genetic Biology  1994 
BS  University of Paris XI, FRANCE  Molecular Biology and Genetics  1993 
My research focuses on the analysis of complex behaviors in the fruit-fly, relevant to neuropsychiatric illnesses such as schizophrenia and depression. I have developed new paradigms to study social behavior. The results of my will allow the identification of the genetics and neural substrates required for social response in flies. I hypothesize that some of the genes and cellular mechanisms involved in tuning a complex nervous system to recognize a similar animal may be shared between humans and flies. To learn more: - Read about my work in the magazine "Discovery": http://www.york.cuny.edu/academics/academic-affairs - Discover one of my students: Robert Fernandez http://www.york.cuny.edu/news/biotech-major-set-for-summer-at-princeton-and-research-day-at-columbia - Listen to a presentation, delivered through the York College Provost lecture series: http://www.youtube.com/watch?v=_dqwppa0UiA&feature=youtube_gdata
Areas of Expertise:
Biology
Genetics
Molecular Biology
Behavior
Drosophila
Articles in Field Of Expertise:

Simon AF, Salazar E, Chou M-T, Nicholson T, Saini N, Metchev S and Krantz DE. "A simple assay to study social behavior in Drosophila: measurement of social space within a group." Genes, Brain and Behavior. 11 2012: 243-252.

Lawal HO, Chang H-Y, Terrell AN, Brooks ES, Pulido D, Simon AF, and Krantz DE. "The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons." Neurobiology of Disease. 40(1) 2010: 102-112.

Simon AF, Daniels R, Romero-Calderón R, Grygoruk A, Chang H-Y, Rod Najibi, Shamouelian D, Salazar E, Solomon M, Larry C. Ackerson LC, Maidment NT, DiAntonio A and Krantz DE.. "Drosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin." Genetics. 181(2) 2009, Feb: 525-41.

Romero-Calderón R, Uhlenbrock G, Borycz J, Simon AF, Grygoruk A, Yee SK, Shyer A, Ackerson LC, Maidment NT, Meinertzhagen IA, Hovemann BT, Krantz DE.. "A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system." PLoS Genetics. 4 (11) 2008, Nov: .

Simon AF, Krantz DE. "Road Rage and Fruit Fly." Nature Genetics. 39 2007, May: 581.

Romero-Calderón R, Shome RM, Simon AF, Daniels RW, DiAntonio A, Krantz DE. "A Screen For Neurotransmitter Transporters Expressed In The Visual System Of Drosophila melanogaster Identifies Three Novel Genes." Developmental Neurobiology. 67 2007, Apr: 550-69.

Simon AF, Liang DT, Krantz DE. "Differential decline in behavioral performance of Drosophila melanogaster with age." Mechanisms Of Ageing And Development. 127 2006, Jul: 647-651.

Suh GSB, Wong AM, Hergarden AC, Wang JW, Simon AF, Benzer S, Axel R, Anderson DJ. "A single population of sensory neurons mediates an innate avoidance behavior in drosophila." Nature. 431 2004, Oct: 854-59.

Brummel T, Ching A*, Seroude L, Simon AF, Benzer S. "Drosophila lifespan enhancement by exogenous bacteria." Proceedings Of The National Academy Of Sciences Of The United States Of America. 101 2004, Aug: 12974–12979.

Simon AF, Shih C, Mack A, Benzer S. "Steroid control of longevity In Drosophila melanogaster." Science. 299 2003, Feb: 1407-1410.

Simon AF, Hitier R, Savary F, Preat T. "No-bridge and linotte act jointly at the interhemispheric junction to build up the adult central brain of drosophila melanogaster." Mechanisms Of Development. 99 2000, Dec: 93-100.

Simon AF, Boquet I, Synguelakis M, Preat T. "The Drosophila putative kinase linotte (derailed) prevents central brain axons from converging, on a newly described interhemispheric ring." Mechanisms Of Development. 76 1998, Aug: 45-55.

Presented Papers, Lectures, and Exhibitions and Performances:

" Fruit-fly social behavior " July 2012: York College Summer Research Program For High School, Undergraduate and Graduate Students..

" “Don’t stand so close to me”: Using the fruit-fly to understand the genetic basis of social interactions " March 2012: York College Provost Lecture Series.

" “Don't stand so close to me": Study of social space in the fruit-fly. " November, 14 2011: Invited seminar - Columbia University of New-York, Department of Pharmacology, Center for Molecular Recognition and in Physiology & Cellular Biophysics.

" “Don't stand so close to me": Study of social space in the fruit-fly. " October 26, 2011: Invited talk - St John’s University, Biology Department.

" “Calibrated Peer Review™ (CPR): a free web-based written assignment tool " Fall 2011: poster for the York College 4th Annual Day of Assessment and CETL Poster Session: “How Do You Know What They Know? Increasing Formative Assessment”..

" IT Services for Faculty " Spring 2011: YC101 workshop, for first year Faculty.

" Dealing with Student Incivility” " Fall 2010: workshop - York College Center for Excellence in Teaching and Learning.

" A New Simple Assay To Study Social Behavior In The Fruit-fly: Measurement Of Social Space " 2010: Invited talk - Long Island University CW Post.

" “alibrated Peer-Review: a free web-based written assignment tool " 2010: Workshop - York College Center for Excellence in Teaching and Learning workshop.

" York IT Resources " 2010: YC101 workshop, for first year Faculty.

" Genetics of Aggregation, a Basic Adaptive Behavior in Drosophila. Neurobiology Of Drosophila, " 2009: Meeting abstract - Neurobiology Of Drosophila, Cold Spring Harbor Laboratories.

" New paradigm for studying social behavior in Drosophila (fruit fly): Exploring genetic basis of social deficits in autism " 2007: Invited talk - UCLA CART Autism Affinity Group, Year 2 Pilot Grants.

" Steroid control of longevity in Drosophila melanogaster " 2005: Invited talk - The Endocrine Society’s 87th Annual meeting..

" Steroid control of longevity in Drosophila melanogaster " 2002: Invited talk - UCLA-CALTECH Drosophila meeting.

" A new paradigm to study social behavior " 2007: Oral Presentation - 48th Annual Drosophila Research Conference, Philadelphia.

" A new laboratory assay to study social behavior in Drosophila melanogaster " 2006: Oral Presentation - Behavioral Ecology Lunch, UCLA.

" Brain Behavior and Immune system in the fruit fly " 2004: Oral Presentation - UCLA Cousins Center for Psychoneuimmunology.

" Behavior, steroids and aging " 2004: Oral presentation - UCLA Hatos Center for Neuropharmacology.

" Steroid control of longevity in Drosophila melanogaster " 2002: Oral Presentation - Caltech 2W5F seminar.

" Steroid control of longevity in Drosophila melanogaster " 2002: Oral Presentation - Ecdysone workshop at the 43rd Annual Drosophila Research Conference, San Diego.

" Genetic Interactions At The Interhemispheric Junction Regulate Central Brain Postembryonic Development " 1999: Oral Presentation by Thomas Preat - 16th European. Drosophila Research Conference, Zurich (Switzerland).

" Implication Of The Linotte (Lio) Gene In Drosophila Brain Development " 1996: Oral Presentation - 6th European symposium on Drosophila neurobiology, Regensburg (Germany).

" Genetic Dissection Of Brain Development In Drosophila " 1996: Oral Presentation by Thomas Preat - Symposium de l’association pour la neuro psycho pharmacologie: “ Neurogenesis: from Egg to Brain ”, Paris (France).

Professional Honors, Prizes, Fellowships:

Featured undergraduate student Robert Fernandez: Biotech major set for summer at Princeton and Research Day at Columbia http://www.york.cuny.edu/news/biotech-major-set-for-summer-at-princeton-and-research-day-at-columbia: Spring 2012.

Featured faculty on the York College publication “Discovery” http://www.york.cuny.edu/academics/academic-affairs: Spring 2012.

PSC-CUNY Research Award: 2012-2013.

PSC-CUNY Research Award: 2011-2012.

PSC - CUNY Research Award: 2010-2011.

PSC - CUNY Research Award: 2009-2010.

Gender Equity Project Grant Writing Assistance Program: Spring 2009.

Young Investigator Award: Genetics of Aggregation, a Basic Adaptive Social Behavior in Drosophila from the National Alliance for Research on Schizophrenia and Depression (NARSAD): 2007-2009.

Pilot funds from a National Institute of Mental Health (NIMH) grant to the CART: Recognition of social contact in Drosophila. Proposal #10SIM2005 from the UCLA Center for Autism Research and Treatment (CART): 2005-2006.

Training support: Investigation of the role of monoamine and steroid pathways in modulation of behavior, the stress response and the immune response in Drosophila from the UCLA Cousins Center for Psychoneuroimmunology: 2005-2006.

Winning Research proposal on Human Creativity: Study of Brain basis of the creative process, using Williams’ syndrome as a model from the Tennenbaum Family Interdisciplinary Center, at the UCLA Neuropsychiatric Institute's: July 2003.

Grant: Study of the long-lived mutants of the ecdysone receptor in Drosophila melanogaster form the Association For Aging Research: 2001-2003.

Postdoctoral fellowship: Involvement of steroid hormonal pauses of aging adults in brain degenera from the The John Douglas French Alzheimer’s Foundation: 1999-2001.

Certificate of Appreciation from the Freshman Summer Institute for diligent work, enthusiastic participation, and creative thinking in the Study of the physiology of a long-lived fly: does it live longer? from the Caltech Office for Minority Students: 2002.

Final 6 months of Doctoral research: Study of the role of the Drosophila gene linotte, incoding a tyrosine receptor kinase homologous to the human gene RYK, in the central brain development from the French foundation for medical research: 1998.

Doctoral research: Study of a gene involved in memory and development of the brain in Drosophila melanogaster: the gene linotte from the French Ministry of Research: 1994-1997.

Other Professional Activities and Public Service:

Member of the Genetic Society of America: 1999-present.

Research Consultant for Santa Monica College, CA: Spring 2007-present.

Manuscripts reviewer for Neurobiology of Aging and Experimental Gerontology: 2004-2008.

Fellowships reviewer for The John Douglas French Alzheimer’s Foundation: 2000-2008.

Creator and organizer of a seminar series 2W5F at Caltech (Worms, Weeds and Flies, Fins, Flippers, Fur, and Feathers): 2000-2002.

Active Member of the Career Committee of the UCLA Society for Postdoctoral scholars: 2005-2008.

Founding member and Leader of the Welcoming Committee of the Caltech Postdoctoral association: 2001-2003.

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Simon, Anne
 

Simon, Anne
Assistant Professor
Biology