- Experts Contact
- For additional information contact Marcia Moxam-Comrie, Marketing Communications Office of Institutional Advancement, Rm 2H03 94-20 Guy R. Brewer Blvd. Jamaica, NY 11451 718-262-2354 (office)/ 718-262-2326 (fax) e-mail: firstname.lastname@example.org
Fearnley, StephenFearnley, Stephen
- Areas of Expertise:
- Organic Synthesis
- Organic Reactions
- Natural Products
As a synthetic organic chemist, my research involves development of new methodology for the construction of bioactive natural products: alkaloids, cyclic ether arrays, & C-glycosides. Current studies include:
• Investigation & use of oxazolone as a useful heterocyclic scaffold for alkaloid synthesis - studies of intramolecular Diels-Alder reactions with oxazolone as dienophile.
• Novel organosilane chemistry for approaches to bioactive ethers - concise assembly of cis-fused bicyclic ether arrays via intramolecular attack of vinylsilanes at tethered oxocarbenium ions. A related silyl-activated Friedel-Krafts process requires an unusual combination of electronic & steric effects.
Recently completed targets include 2-epi-pumiliotoxin C & deoxyaltholactone. Similar approaches to gephyrotoxin & dysiherbaine are underway.
Degree Institution Field Dates PhD University of Salford Organic Chemistry 1992 BS Sheffield City Polytechnic Applied Chemistry 1988