Office Location: AC-4E03F
Degree Institution Field Dates PhD University of Massachusetts Medical School Biomedical Sciences 1996 BS University of Massachusetts Dartmouth Biology 1985
My background and current research focus on the role of RNA-binding proteins in the regulation of important developmental events using Drosophila melanogaster as a model system. Although RNA-binding proteins have been shown to regulate the translation, stability, and localization of mRNAs during development, little is known of potential regulation at the level of transport and splicing events in the nucleus. I am currently focusing on identifying RNA targets of a nuclearly localized RNA-binding protein called Lark that is required for progression through oogenesis. It is likely that Lark is required at the level of RNA-splicing or nuclear-cytoplamic transport.
Areas of Expertise
- Developmental Genetics
Articles in Field Of Expertise
McNeil, G.P., Schroeder, A.J., Roberts, M.A., and Jackson, F.R.. ") Genetic analysis of functional domains within the LARK RNA-binding protein.." Genetics. 159 2001: 229-240.
McNeil, G.P., Smith, F., and Galioto, R. "The Drosophila RNA-binding protein Lark is required for the." genesis. 40 2004: 90-100.
Lopatto et al.. "Genomics Education Partnership." Science. 322 2008: 684-685.
McNeil, G.P., Kaur, M., Purrier, S., and Kang, R.. "The Drosophila RNA-binding protein Lark is required for localization of Dmoesin to the oocyte cortex during oogenesis." Dev Genes Evol. 219 2009: 11-19.
Shaffer CD, Alvarez C, Bailey C, Barnard D, Bhalla S, Chandrasekaran C, Chandrasekaran V, Chung HM, Dorer DR, Du C, Eckdahl TT, Poet JL, Frohlich D, Goodman AL, Gosser Y, Hauser C, Hoopes LL, Johnson D, Jones CJ, Kaehler M, Kokan N, Kopp OR, Kuleck GA, McNeil G, Moss R, Myka JL, Nagengast A, Morris R, Overvoorde PJ, Shoop E, Parrish S, Reed K, Regisford EG, Revie D, Rosenwald AG, Saville K, Schroeder S, Shaw M, Skuse G, Smith C, Smith M, Spana EP, Spratt M, Stamm J, Thompson JS, Wawersik M, Wilson BA, Youngblom J, Leung W, Buhler J, Mardis ER, Lopatto D, Elgin SC.. "The genomics education partnership: successful integration of research into laboratory classes at a diverse group of undergraduate institutions.." CBE Life Sci Educ.. 9 2010: 55-69.
Emerson JA, Silver Key SC, Alvarez CJ, Mel S, McNeil G, Saville KJ, Leung W, Shaffer CD, Elgin SCR.. "Introduction to the Genomics Education Partnership and Collaborative Genomics Research in Drosophila.." Tested Studies for Laboratory Teaching. Proceedings of the Association for Biology Laboratory Education. 34 2013: 135-165.
Shaffer CD., ...McNeil GP,... Elgin SC.. "A Course-Based Research Experience: How Benefits Change with Increased Investment in Instructional Time." CBE Life Sci Educ. 13 2014: 111-130.
Huang Y., McNeil GP, and FR Jackson. "Translational Regulation of the DOUBLETIME/CKIδ/ε Kinase by LARK Contributes to Circadian Period Modulation." PLOS Genetics. 10 2014: 1-13.
Lopatto D., ...McNeil G., ... SCR Elgin. "A central support system can facilitate implementation and sustainability of a classroom-based undergraduate research experience (CURE) in genomics." CBE Life Sci Educ. in press: .
Presented Papers, Lectures, and Exhibitions and Performances
" Identification and characterization of in vivo targets of Lark, an RNA-binding protein required during Drosophila oogenesis " December 1, 2010: Queens College.
" Identification and characterization of in vivo targets of Lark, an RNA-binding protein required during Drosophila oogenes " December 3, 2010: Graduate Center.
" "Characterization of RNA targets of the nuclear RNA-binding protein Lark during Drosophila oogenesis." " April 2011: Fordham University.
" “Lark, a multifunctional RNA-binding protein affecting a diverse set of processes during Drosophila development”. " April 2012: St John's University.
Professional Honors, Prizes, Fellowships
King of Queens Award (Queens Courier): November 2012.
NIH, Characterization of RNA targets of the RNA-binding protein Lark during oogenesis. 2010-2013: $300,000.
NIH, Characterization of RNA targets for the RNA-binding protein Lark during oogenesis. 2005-2009: $344,596.
NIH, Role of a Drosophila RNA-binding protein in oogenesis. 2002-2004: $220,082.
NIH, T36 MARC grant application in collaboration with Dr. Andrew Campbell at Brown University.. Funding pending: .
Other Professional Activities and Public Service
External Advisory Board for the ISMD Program at Brown University: 2009-present.
Editorial Board of ISRN Molecular Biology Journal: 2011-presemt.
Editorial Board of ISRN Entomology: 2012-present.